HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 3-(1-Methyl-2-pyrrolylcarbonyl)propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Ethyl Acrylate | HCID 8821 | — |
| Edukt | 1-Methyl-1H-pyrrole-2-carbaldehyde | HCID 14504 | — |
| Edukt | (1-methyl-1H-pyrrol-2-yl)(morpholin-4-yl)acetonitrile | HCID 20529962 | — |
| Produkt | 3-(1-Methyl-2-pyrrolylcarbonyl)propionic acid | HCID 12504054 | — |
Reaktionsschritte
As for Example 6, 1-methyl-2-pyrrolecarboxaldehyde is converted to α-(1-methyl-2-pyrrolyl)-4-morpholineacetonitrile. The preceding compound is reacted with ethyl acrylate and the resulting 1,4-addition product is heated at 100° C. with 6 N hydrochloric acid to give 3-(1-methyl-2-pyrrolylcarbonyl)propionic acid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04299769 |
| Quelldatensatz | uspto-grants-1981_11 |
| ORD ID | ord-4913ddbca2124d7e89083018fe061be3 |
| Quellennotiz | uspto-grants-1981_11 |