Tiopronin → HCID 56608455, Verbindung

HRID 1155144

Reaktionsgleichung

Reaktionsgleichung von HRID 1155144
[SH:1][CH:2]([CH3:10])[C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4].[C:11]1([C:17]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>FC(F)(F)C(O)=O>[C:17]([S:1][CH:2]([CH3:10])[C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4])([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

Komponenten

4

Edukt 2

HCID 5483TioproninHCID 6457Triphenylcarbinol

Produkt 1

HCID 56608455HCID 56608455, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6422Trifluoroacetic acidLösungsmittel

Versuchsvorschrift

To a solution of alpha-mercaptopropionyl glycine (50 g; 0.307 moles) in 300 ml of trifluoroacetic acid, were added 79.9 g (0.307 moles) of triphenylcarbinol. The thus obtained solution was kept under stirring at room temperature for 15 minutes. The excess of trifluoroacetic acid was removed by evaporation and the residue taken up with ether. Filtration yielded a white solid, which was then washed with ether and dried in vacuo to constant weight.

Aufarbeitung

  1. customThe excess of trifluoroacetic acid was removed by evaporation
  2. filtrationFiltration
  3. customyielded a white solid, which
  4. washwas then washed with ether
  5. customdried in vacuo to constant weight

Quellen und Nachweise

ORD-Eintrag
ord-c35d75ee4e0a4b42801e8a21fcc5aea0
Quelldatensatz
uspto-grants-1981_11
Patentnummer
US04299842

Verknüpfte Notizen

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