Toluene → N-[5-tert-Butyl-4-(hexadecyloxy)-2-hydroxyphenyl]acetamide

HRID 1156565Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1156565
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[CH:7][C:6]=1[OH:28])(=[O:3])[CH3:2].[C:29]1([CH3:35])[CH:34]=CC=C[CH:30]=1.C=C(C)C>CCCCCC>[C:1]([NH:4][C:5]1[CH:10]=[C:9]([C:29]([CH3:35])([CH3:34])[CH3:30])[C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[CH:7][C:6]=1[OH:28])(=[O:3])[CH3:2]

Komponenten

5

Edukt 3

HCID 1140TolueneHCID 8255IsobutyleneHCID 13765207N-[4-(Hexadecyloxy)-2-hydroxyphenyl]acetamide

Produkt 1

HCID 20257269N-[5-tert-Butyl-4-(hexadecyloxy)-2-hydroxyphenyl]acetamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8058HexaneLösungsmittel

Versuchsvorschrift

A mixture of 30.0 g of 2-acetylamino-5-hexadecyloxyphenol, 20.0 g of Amberlyst 15 (produced by Rohm & Haas Co., U.S.A.) and 300 ml of toluene was stirred while heating at 80°-90° C., during which isobutene was bubbled therethrough for 5 hours. The reaction solution was filtered to remove solids and the filtrate was condensed. On adding 350 ml of n-hexane to the residue, crystals precipitated. The crystals were collected by filtration. 23.5 g of 2-acetylamino-4-tert-butyl-5-hexadecyloxyphenol was obtained.

Aufarbeitung

  1. customwas bubbled
  2. filtrationThe reaction solution was filtered
  3. customto remove solids
  4. customcondensed
  5. customprecipitated
  6. filtrationThe crystals were collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-77ca0793105e4a4bbd01efea5339e4ed
Quelldatensatz
uspto-grants-1982_06
Patentnummer
US04336322

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