2,3-Dichloro-4-methoxycinnamic acid → 3-(2,3-Dichloro-4-methoxyphenyl)-propanoic acid

HRID 1157040

Reaktionsgleichung

Reaktionsgleichung von HRID 1157040
[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([O:14][CH3:15])[CH:10]=[CH:9][C:3]=1[CH:4]=[CH:5][C:6]([OH:8])=[O:7]>O1CCCC1.[Pt]>[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([O:14][CH3:15])[CH:10]=[CH:9][C:3]=1[CH2:4][CH2:5][C:6]([OH:8])=[O:7]

Komponenten

4

Edukt 1

HCID 536752552,3-Dichloro-4-methoxycinnamic acid

Produkt 1

HCID 128069603-(2,3-Dichloro-4-methoxyphenyl)-propanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23939PlatinumKatalysatorHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

2,3-Dichloro-4-methoxycinnamic acid (200.8 g., 0.813 mole) is dissolved in tetrahydrofuran (1600 ml.) and 5% platinum on charcoal (16.3 gm.) is added. The mixture is divided into 8 separate units and each is placed in a Parr hydrogenation apparatus in an atmosphere of hydrogen at an initial pressure of 50 p.s.i. Upon shaking, the time required for the reduction of each batch is 35 to 60 minutes.

Aufarbeitung

  1. customseparate units

Quellen und Nachweise

ORD-Eintrag
ord-73b05e8912c34fedb299d922f926aea6
Quelldatensatz
uspto-grants-1982_06
Patentnummer
US04337354

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