Formamidine acetate → HCID 178435739, Verbindung

Beteiligte Stoffe

Reaktionsschritte

A solution of 3-(8-ethyl-naphthalen-1-yl)-propane-1,2-diamine (60 mg) in EtOH (6 ml) was treated at r.t. under an argon atmosphere with formamidine acetate (30 mg). The reaction mixture was stirred at r.t. overnight, then concentrated. The crude product was purified by column chromatography (silica gel; eluent: CH2Cl2→CH2Cl2/MeOH 9:1) to give (RS)-4-(8-ethyl-naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole (38 mg) as light yellow gum. MS (ISP): 239.3 ((M+H)+).

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