HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-[tert-butoxycarbonyl]-L-serine → (R)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-[tert-butoxycarbonyl]-L-serine | HCID 98766 | — |
| Edukt | (R)-2-tert-butoxycarbonylamino-3-hydroxy propionic acid | HCID 637603 | — |
| Edukt | (S)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride | HCID 18599716 | — |
| Produkt | (R)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride | HCID 69195062 | — |
Reaktionsschritte
(R)-3-amino-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride salt was prepared from N-t-butyloxycarbonyl-D-serine by the procedures described in Itoh, et al., Chem. Pharm. Bull. 1986, 34, 1128–1147 for the preparation of (S)-3-amino-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride salt from N-t-butyloxycarbonyl-L-serine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07098235B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-7c264e9779284e15bdd86025c4faf7dd |
| Quellennotiz | uspto-grants-2006_08 |