O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine → 1-Amino-4-[(phenylmethyl)oxy]pyridinium 2,4,6-trimethylbenzenesulfonate

HRID 1159944Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1159944
[NH2:1][O:2][S:3]([C:6]1[C:11]([CH3:12])=[CH:10][C:9]([CH3:13])=[CH:8][C:7]=1[CH3:14])(=[O:5])=[O:4].[C:15]1([CH2:21][O:22][C:23]2[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(Cl)Cl>[CH3:12][C:11]1[CH:10]=[C:9]([CH3:13])[CH:8]=[C:7]([CH3:14])[C:6]=1[S:3]([O-:5])(=[O:4])=[O:2].[NH2:1][N+:26]1[CH:27]=[CH:28][C:23]([O:22][CH2:21][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:24][CH:25]=1

Komponenten

4

Edukt 2

HCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamineHCID 123288284-(Benzyloxy)pyridine

Produkt 1

HCID 866187801-Amino-4-[(phenylmethyl)oxy]pyridinium 2,4,6-trimethylbenzenesulfonate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

A solution of 2-[(aminooxy)sulfonyl]-1,3,5-trimethylbenzene (4.05 g, 18.8 mmol) in DCM (60 mL) was cooled to 0° C. 4-[(Phenylmethyl)oxy]pyridine (2.91 g, 15.7 mmol) in DCM (2 mL) was added dropwise. Following complete addition, the mixture was stirred at rt for 45 min. The reaction mixture was evaporated under reduced pressure to give crude white foam.

Aufarbeitung

  1. additionaddition
  2. customThe reaction mixture was evaporated under reduced pressure
  3. customto give crude white foam

Quellen und Nachweise

ORD-Eintrag
ord-cef7e192d3b84e339fce7f47090bd9f6
Quelldatensatz
uspto-grants-2010_10
Patentnummer
US07812022B2

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