Bromopentamethylbenzene → Racemic 3-{4-[1-(2,3,4,5,6-pentamethyl-phenoxy)-5,5,5-trifluoro-pentyl]-benzoylamino}-propionic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Bromopentamethylbenzene	HCID 78831	—
Edukt	3-(4-{5,5,5-Trifluoro-1-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-phenoxy]-pentyl}-benzoylamino)-propionic acid methyl ester	HCID 67153418	—
Produkt	Racemic 3-{4-[1-(2,3,4,5,6-pentamethyl-phenoxy)-5,5,5-trifluoro-pentyl]-benzoylamino}-propionic acid	HCID 87288608	—

Reaktionsschritte

The title compound is prepared in a manner substantially similar to Example 359 starting from 3-(4-{5,5,5-trifluoro-1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pentyl}-benzoylamino)-propionic acid methyl ester and 1-bromo-2,3,4,5,6-pentamethyl-benzene. MS: 554.2 [M−H]−.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07816557B2
Quelldatensatz	uspto-grants-2010_10
ORD ID	ord-90e90cf652a34964b18496a3a8368406
Quellennotiz	uspto-grants-2010_10