HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-[(4-Hydroxymethyl-phenyl)-methoxy-methyl]-benzonitrile → 3-{[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-methoxy-methyl}-benzonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-[(4-Hydroxymethyl-phenyl)-methoxy-methyl]-benzonitrile | HCID 57438353 | — |
| Edukt | 3-[[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-(tetrahydro-pyran-2-yloxy)-methyl]-benzonitrile | HCID 66699604 | — |
| Produkt | 3-{[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-methoxy-methyl}-benzonitrile | HCID 66699558 | — |
Reaktionsschritte
The title compound is prepared in a similar manner to 3-[[4-(4-acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-(tetrahydro-pyran-2-yloxy)-methyl]-benzonitrile employing 3-[(4-Hydroxymethyl-phenyl)-methoxy-methyl]-benzonitrile to afford 248 mg, 78%, as a colorless oil. LCMS M+1 430.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07816523B2 |
| Quelldatensatz | uspto-grants-2010_10 |
| ORD ID | ord-e86ae1cbac5145a68753c6c04e78cfc7 |
| Quellennotiz | uspto-grants-2010_10 |