4-(Methylthio)aniline → 1-[4-(4-Methylsulfanyl-phenylamino)-6-phenyl-pyrimidin-2-yl]-piperidin-4-ol
Reaktionsgleichung
Cl[C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([N:14]2[CH2:19][CH2:18][CH:17]([OH:20])[CH2:16][CH2:15]2)[N:3]=1.[CH3:21][S:22][C:23]1[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][CH:24]=1>>[CH3:21][S:22][C:23]1[CH:28]=[CH:27][C:26]([NH:29][C:2]2[CH:7]=[C:6]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[N:5]=[C:4]([N:14]3[CH2:19][CH2:18][CH:17]([OH:20])[CH2:16][CH2:15]3)[N:3]=2)=[CH:25][CH:24]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared by treating 1-(4-chloro-6-phenyl-pyrimidin-2-yl)-piperidin-4-ol (0.3 g, 1.04 mmol) with 4-methylsulfanyl-phenylamine (0.14 g, 1.04 mmol) according to the procedure described above.
Quellen und Nachweise
- ORD-Eintrag
- ord-48f608e6c8e742f68ba7c17203856727
- Quelldatensatz
- uspto-grants-2010_10