Sodium Hydroxide → HCID 58840902, Verbindung

Reaktionsgleichung

C[O:2][C:3](=[O:22])[CH:4]([O:11][C:12]([NH:14][C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)=[O:13])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[OH-].[Na+]>CO.C1COCC1>[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([NH:14][C:12]([O:11][CH:4]([C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:3]([OH:22])=[O:2])=[O:13])=[CH:16][CH:17]=1

Komponenten

Versuchsvorschrift

Methyl((((4-chlorophenyl)amino)carbonyl)oxy)(phenyl)acetate (0.73 g) obtained in Example 3a) and 1 N sodium hydroxide (3.0 ml) were dissolved in methanol (10 ml) and THF (10 ml), and then mixed at room temperature for 15 hours. The reaction solution was then concentrated under reduced pressure, acidified by adding 1 N hydrochloric acid to the concentrated solution, and then the precipitate was collected by filtration and washed with water to obtain the title compound as pale brown powder (0.62 g, 89%).