Potassium Carbonate → HCID 178502891, Verbindung

Beteiligte Stoffe

Reaktionsschritte

For example, 3-chloro-5-trifluoromethylpyridine-2-carboxylic acid is reacted with thionyl chloride whereby 3-chloro-5-trifluoromethylpicolinoyl chloride can be obtained. This compound is reacted with O-methylhydroxyamine hydrochloride at room temperature for 4 hours in the presence of potassium carbonate to obtain N-methoxy-3-chloro-5-trifluoromethylpyridine-2-carboximidic acid which is then reacted with O,O-diethylthionophospholic acid diester chloride at 50° C. for 24 hours in the presence of potassium carbonate to thereby obtain O,O-diethyl-O-(N-methoxy-3-chloro-5-trifluoromethylpyridine-2-carboximidoyl)thionophosphate (nD16.0 = 1.5054).

Herkunft & Nachweise