Chlorosulfonic acid → 4-Methoxy-2,3,5,6-tetramethylbenzenesulfonyl chloride

HRID 1164286

Reaktionsgleichung

Reaktionsgleichung von HRID 1164286
[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[C:4]([CH3:10])[C:3]=1[O:11][CH3:12].[Cl:13][S:14](O)(=[O:16])=[O:15]>ClCCl>[CH3:12][O:11][C:3]1[C:4]([CH3:10])=[C:5]([CH3:9])[C:6]([S:14]([Cl:13])(=[O:16])=[O:15])=[C:7]([CH3:8])[C:2]=1[CH3:1]

Komponenten

4

Edukt 2

HCID 24638Chlorosulfonic acidHCID 2786643-Methoxy-1,2,4,5-tetramethylbenzene

Produkt 1

HCID 159175204-Methoxy-2,3,5,6-tetramethylbenzenesulfonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

In 600 ml of dichloromethane was dissolved 10.0 g of 2,3,5,6-tetramethylanisole, followed by addition of a solution (400 ml) of 12 ml of chlorosulfonic acid in dichloromethane at -5°~-10° C. The mixture was kept stirred for 2 hours and the reaction mixture was poured into ice-5% aqueous NaHCO3. The organic layer was washed with water and dried over magnesium sulfate. The solvent was distilled off and the residue was crystallized from n-hexane and filtered.

Aufarbeitung

  1. washThe organic layer was washed with water
  2. dry with materialdried over magnesium sulfate
  3. distillationThe solvent was distilled off
  4. customthe residue was crystallized from n-hexane
  5. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-87c3f7ec7fab4194a04023d4475c0f29
Quelldatensatz
uspto-grants-1983_01
Patentnummer
US04368150

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