N-benzoyl-N'-(2-phenoxyphenyl)thiourea → (2-Phenoxyphenyl)thiourea

HRID 1164517Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1164517
[O:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]([NH:17]C(=O)C1C=CC=CC=1)=[S:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[OH-].[Na+].CO>[O:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]([NH2:17])=[S:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 1

HCID 1488843N-benzoyl-N'-(2-phenoxyphenyl)thiourea

Produkt 1

HCID 1479735(2-Phenoxyphenyl)thiourea

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 14798Sodium HydroxideLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

Thus produced 1-(2-phenoxyphenyl)-3-benzoylthiourea was dissolved in a mixture of 10% aqueous sodium hydroxide (660 ml) and methanol (530 ml) at 50° C. The reaction mixture was stirred for 30 minutes at 50° C. and then cooled with ice to give crystals, which were separated by filtration, washed with water and dried to give 1-(2-phenoxyphenyl)thiourea.

Aufarbeitung

  1. temperaturecooled with ice
  2. customto give crystals, which
  3. customwere separated by filtration
  4. washwashed with water
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-cbc329f34f34434583a202475ee9d3a7
Quelldatensatz
uspto-grants-1983_01
Patentnummer
US04370340

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