Nitric Acid → 1,4-Dichloro-2-cyclohexyl-5-nitrobenzene

HRID 1164521

Reaktionsgleichung

Reaktionsgleichung von HRID 1164521
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[CH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.[N+:15]([O-])([OH:17])=[O:16]>S(=O)(=O)(O)O>[Cl:1][C:2]1[CH:7]=[C:6]([N+:15]([O-:17])=[O:16])[C:5]([Cl:8])=[CH:4][C:3]=1[CH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Komponenten

4

Edukt 2

HCID 944Nitric AcidHCID 130971441,4-Dichloro-2-cyclohexylbenzene

Produkt 1

HCID 130971451,4-Dichloro-2-cyclohexyl-5-nitrobenzene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel2×

Versuchsvorschrift

To a solution of 1,4-dichloro-2-cyclohexylbenzene (12.0 g) in conc. sulfuric acid (15 ml) was added dropwise a mixture of nitric acid (d=1.42, 4 ml) and conc.sulfuric acid (6 ml) with stirring under ice-cooling. After the stirring was continued for 10 minutes, ice-water was added to the reaction mixture to give an oily residue, which was extracted with ether, washed with water, dried over magnesium sulfate and concentrated under reduced pressure. The resultant oily residue was distilled under reduced pressure to give 1,4-dichloro-2-cyclohexyl-5-nitrobenzene (10.0 g).

Aufarbeitung

  1. temperaturecooling
  2. customto give an oily residue, which
  3. extractionwas extracted with ether
  4. washwashed with water
  5. dry with materialdried over magnesium sulfate
  6. concentrationconcentrated under reduced pressure
  7. distillationThe resultant oily residue was distilled under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-1f0da45e7bb24e9f84114a89d982f605
Quelldatensatz
uspto-grants-1983_01
Patentnummer
US04370340

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