Aluminum(III) Chloride → HCID 178454735, Verbindung

HRID 1164799

Reaktionsgleichung

Reaktionsgleichung von HRID 1164799
[OH:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:11][CH:12]([CH2:16][C:17]([O:19]C)=[O:18])[C:13](Cl)=[O:14].[Cl-].[Al+3].[Cl-].[Cl-]>C(=S)=S>[C:17]([CH2:16][CH:12]([CH3:11])[C:13]([C:8]1[CH:9]=[CH:10][C:4]2[N:3]=[C:2]([OH:1])[NH:6][C:5]=2[CH:7]=1)=[O:14])([OH:19])=[O:18]

Komponenten

5

Edukt 3

HCID 6451240Aluminum(III) ChlorideHCID 14403282Methyl 4-chloro-3-methyl-4-oxobutanoateHCID 178517141HCID 178517141, Verbindung

Produkt 1

HCID 178454735HCID 178454735, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6348Carbon DisulfideLösungsmittel

Versuchsvorschrift

Carbon disulfide (90 ml), 2-hydroxybenzimidazole (4.1 g) and 2-methyl-3-carbomethoxy propionyl chloride (5 g) are added to aluminum chloride (20.3 g) under nitrogen. The resulting mixture is refluxed for about 45 hours, quenched with ice cold 6N HCl and the acidic mixture filtered. The filtered solid is washed with water and dried in vacuo, affording the desired product as a solid, M.P. 223° C. (dec).

Aufarbeitung

  1. temperatureThe resulting mixture is refluxed for about 45 hours
  2. customquenched with ice cold 6N HCl
  3. filtrationthe acidic mixture filtered
  4. washThe filtered solid is washed with water
  5. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-8307db374afe4216886b389ebf9ee85c
Quelldatensatz
uspto-grants-1990_03
Patentnummer
US04906630

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