Potassium Hydroxide → 4-chloro-2-(4-chlorophenyl)-5-(4-trifluoromethylbenzyloxy)-3(2H)-pyridazinone

Beteiligte Stoffe

Reaktionsschritte

In 30 ml of N,N-dimethylformamide were dissolved 1.0 g (3.6 m mol) of 2-(4-chlorophenyl)-4,5-dichloro-3(2H)-pyridazinone and 0.64 g (3.6 m mol) of p-trifluoromethylbenzyl alcohol, and thereto was added 0.24 g of powdery potassium hydroxide. The reaction mixture was stirred at room temperature for one day. Then, the procedures in Synthesis Example 2 were repeated to give 900 mg of the intended compound.

Herkunft & Nachweise