Bromine → 2-Bromo-1-(4-methoxyphenyl)-2-(3-pyridyl)ethanone hydrobromide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

1-(4-Methoxyphenyl)-2-(3-pyridyl)ethanone (6.85 g) was dissolved in acetic acid (36 mL), bromine (1.7 mL) was added to the solution and the resulting mixture was stirred at 80° C. for 3 h. After the mixture was cooled with ice-water, the crude crystalline mass was collected by filtration. The crude crystalline was recrystallized from ethanol-ethyl ether to afford the title compound (10.4 g, yield 89%).

Herkunft & Nachweise