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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1169985Erstellt: 24. Oktober 2026

Stannous Chloride → 2-Amino-5-fluorobenzonitrile

https://huagongshe.com/de/reaction/1169985

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktStannous ChlorideHCID 24479—
Edukt5-Fluoro-2-nitrobenzonitrileHCID 3756467—
LösungsmittelHydrochloric AcidHCID 313—
Produkt2-Amino-5-fluorobenzonitrileHCID 2737704—

Reaktionsschritte

The title compound was synthesized from commercially available 2-nitro-5-fluorobenzenecarbonitrile via reduction with SnCl2 in concentrated HCl as previously described in the following reference which is herein incorporated by reference in its entirety for all purposes as if fully set forth herein: Hunziker, F. et al. Eur. J. Med. Chem., Chim. Ther. 1981, 16(5), 391. GC/MS m/z: 136.1 (M+, 100%), Rt 8.87 minutes.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07825132B2
Quelldatensatzuspto-grants-2010_11
ORD IDord-01cbccf3425e409f9d5ffa2a1318af5c
Quellennotizuspto-grants-2010_11