Tetrahydrofuran → Chloropropyldimethylvinylsilane

HRID 1170068

Reaktionsgleichung

Reaktionsgleichung von HRID 1170068
C([Mg]Br)=C.[Cl:5][CH2:6][CH2:7][CH2:8][Si:9]([CH3:12])(C)Cl.[CH2:13]1[CH2:17]OC[CH2:14]1>>[Cl:5][CH2:6][CH2:7][CH2:8][SiH2:9][CH:12]=[C:13]([CH3:17])[CH3:14]

Komponenten

4

Edukt 3

HCID 8028TetrahydrofuranHCID 82765Silane, chloro(3-chloropropyl)dimethyl-HCID 178418507HCID 178418507, Verbindung

Produkt 1

HCID 131715857ChloropropyldimethylvinylsilaneAusbeute 66,49 %

Versuchsvorschrift

To a stirred solution of 1 M vinyl magnesium bromide in THF (9.1 L), 3-chloropropyl dimethylchlorosilane (1.5 Kg) was added over the period of 3 hr through an addition. The reaction mixture stirred further for 2 hr. Added D.M water (9.1 L) and separated the organic layer. The hazy aqueous layer was filtered through hyflo bed and extracted with dichloromethane (3.0 L). The dichloromethane extract was mixed with organic layer and evaporated to dryness to give yellow liquid which was distilled using a Vigreaux column to get pure colorless title product (0.986 Kg)

Aufarbeitung

  1. customAdded D.M water (9.1 L) and separated the organic layer
  2. filtrationThe hazy aqueous layer was filtered through hyflo bed
  3. extractionextracted with dichloromethane (3.0 L)
  4. extractionThe dichloromethane extract
  5. additionwas mixed with organic layer
  6. customevaporated to dryness
  7. customto give yellow liquid which
  8. distillationwas distilled

Quellen und Nachweise

ORD-Eintrag
ord-b4d53911fb1348868ab25b31f34d2f40
Quelldatensatz
uspto-grants-2010_11
Patentnummer
US07825257B1

Verknüpfte Notizen

Wird geladen…