4-[3-(4-Benzyloxy-phenyl)-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-pyridine → 4-[4-Pyridin-4-yl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-yl]-phenol
Reaktionsgleichung
CN1C=C(C2C=CN=CC=2)C(C2C=CC(O)=CC=2)=N1.C([O:27][C:28]1[CH:33]=[CH:32][C:31]([C:34]2[C:38]([C:39]3[CH:44]=[CH:43][N:42]=[CH:41][CH:40]=3)=[CH:37][N:36]([CH2:45][C:46]([F:49])([F:48])[F:47])[N:35]=2)=[CH:30][CH:29]=1)C1C=CC=CC=1>>[N:42]1[CH:43]=[CH:44][C:39]([C:38]2[C:34]([C:31]3[CH:30]=[CH:29][C:28]([OH:27])=[CH:33][CH:32]=3)=[N:35][N:36]([CH2:45][C:46]([F:48])([F:49])[F:47])[CH:37]=2)=[CH:40][CH:41]=1Komponenten
3
Versuchsvorschrift
Following the procedure for the preparation of 4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenol but substituting 4-[3-(4-Benzyloxy-phenyl)-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-pyridine provided the title compound. MS: (M+H m/z=320.1)
Quellen und Nachweise
- ORD-Eintrag
- ord-9b7f754a33ff41e9b6956de0ea79c39f
- Quelldatensatz