Triphenylphosphine → (3-Cyanopropyl)triphenylphosphonium bromide

HRID 1173999

Reaktionsgleichung

Reaktionsgleichung von HRID 1173999
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:20][CH2:21][CH2:22][CH2:23][C:24]#[N:25]>C1(C)C=CC=CC=1>[Br-:20].[C:24]([CH2:23][CH2:22][CH2:21][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)#[N:25]

Komponenten

4

Edukt 2

HCID 11776TriphenylphosphineHCID 214124-Bromobutyronitrile

Produkt 1

HCID 3036619(3-Cyanopropyl)triphenylphosphonium bromideAusbeute 50,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Triphenylphosphine (1.4789 g) was dissolved in anhydrous toluene (44.4 ml) and then added with 4-bromo-butyronitrile (manufactured by Tokyo Kasei Kogyo Co., Ltd.) (834.7 mg), followed by thermal reflux for 22 hours. After the reaction, a precipitated product was filtrated. The precipitate obtained through filtration was washed with toluene and thermally dried under reduced pressure, thereby obtaining the subject compound (1.1697 g) as a white solid.

Aufarbeitung

  1. temperatureby thermal reflux for 22 hours
  2. customAfter the reaction
  3. filtrationa precipitated product was filtrated
  4. customThe precipitate obtained through filtration
  5. washwas washed with toluene
  6. customthermally dried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5d23629626a24808898e5d0bd44810c0
Quelldatensatz
uspto-grants-2010_11
Patentnummer
US07833991B2

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