HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-3-phenylbutanoic acid → 5-chloro-N-[(1S)-1-cyclohexyl-2-hydroxyethyl]thiophene-2-sulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Amino-3-phenylbutanoic acid | HCID 64808 | — |
| Edukt | Alloisoleucine, DL- | HCID 99288 | — |
| Edukt | (alphaS)-alpha-Aminocyclohexaneacetic acid | HCID 736848 | — |
| Edukt | 5-Bromothiophene-2-sulfonyl chloride | HCID 2733924 | — |
| Edukt | 5-Chlorothiophene-2-sulfonyl chloride | HCID 2733925 | — |
| Produkt | 5-chloro-N-[(1S)-1-cyclohexyl-2-hydroxyethyl]thiophene-2-sulfonamide | HCID 12987475 | — |
Reaktionsschritte
The following compounds (Examples 12-17, Table 4) were prepared using 5-chlorothiophene-2-sulfonyl chloride, and 5-bromothiophene-2-sulfonyl chloride with L-cyclohexylglycine, β-methyl-DL-phenylalanine, and L-allo-isoleucine and following the procedure outlined in Example 12.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07842718B2 |
| Quelldatensatz | uspto-grants-2010_11 |
| ORD ID | ord-877127a58e194a7f95648dfb77258d4e |
| Quellennotiz | uspto-grants-2010_11 |