HCID 58884901, Verbindung → HCID 68501458, Verbindung
Reaktionsgleichung
OC1C=CC([CH:8]2[CH:13]([O:14][CH2:15][C:16]3[CH:17]=[CH:18][C:19]4[O:24][CH2:23][C:22](=[O:25])[N:21]([CH2:26][CH2:27][CH2:28][O:29][CH3:30])[C:20]=4[CH:31]=3)[CH2:12][CH2:11][CH2:10][N:9]2[C:32]([O:34][CH2:35][C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[O:33])=CC=1.C1(C)C=CC(S([O:51][CH2:52][CH2:53][O:54][C:55]2[CH:60]=[CH:59][CH:58]=[C:57]([O:61][CH3:62])[CH:56]=2)(=O)=O)=CC=1>>[CH3:62][O:61][C:57]1[CH:56]=[C:55]([CH:60]=[CH:59][CH:58]=1)[O:54][CH2:53][CH2:52][O:51][C:16]1[CH:17]=[CH:18][C:19]([CH:12]2[CH2:11][CH2:10][N:9]([C:32]([O:34][CH2:35][C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[O:33])[CH2:8][CH:13]2[O:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]3[O:24][CH2:23][C:22](=[O:25])[N:21]([CH2:26][CH2:27][CH2:28][O:29][CH3:30])[C:20]=3[CH:31]=2)=[CH:20][CH:31]=1Komponenten
3
Versuchsvorschrift
Analogously to Method I, 0.500 g of benzyl 4-hydroxyphenyl-3-[4-(3-methoxypropyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]piperidinecarboxylate and 0.414 g of 2-(3-methoxyphenoxy)ethyl toluene-4-sulphonate are reacted. The title compound is obtained as a colourless oil. Rf=0.31 (2:1 EtOAc-heptane); Rt=5.51.
Quellen und Nachweise
- ORD-Eintrag
- ord-fc256ac641be4556b4cd317fb5ccc884
- Quelldatensatz
- uspto-grants-2010_11