Trifluoroacetic acid → Methyl-phenyl-carbamic Acid 4-[2-(4-imidazol-1-yl-phenoxy)-ethyl]-phenyl Ester

HRID 1180054

Reaktionsgleichung

Reaktionsgleichung von HRID 1180054
C(O)(C(F)(F)F)=O.[OH:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][C:18](=[O:27])[N:19]([CH3:26])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:13][CH:12]=1.[N:28]1([C:33]2[CH:38]=[CH:37][C:36](O)=[CH:35][CH:34]=2)[CH:32]=[CH:31][N:30]=[CH:29]1>>[N:28]1([C:33]2[CH:38]=[CH:37][C:36]([O:8][CH2:9][CH2:10][C:11]3[CH:12]=[CH:13][C:14]([O:17][C:18](=[O:27])[N:19]([CH3:26])[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=4)=[CH:15][CH:16]=3)=[CH:35][CH:34]=2)[CH:32]=[CH:31][N:30]=[CH:29]1

Komponenten

4

Edukt 3

HCID 6422Trifluoroacetic acidHCID 823151-(p-Hydroxyphenyl)imidazoleHCID 69520342Methyl-phenyl-carbamic Acid 4-(2-hydroxy-ethyl)-phenyl Ester

Produkt 1

HCID 69518942Methyl-phenyl-carbamic Acid 4-[2-(4-imidazol-1-yl-phenoxy)-ethyl]-phenyl EsterAusbeute 62 %

Versuchsvorschrift

The title compound was prepared as its TFA salt in 62% yield as an oil using methyl-phenyl-carbamic acid 4-(2-hydroxy-ethyl)-phenyl ester and 4-imidazol-1-yl-phenol.

Quellen und Nachweise

ORD-Eintrag
ord-6111678472a5460ea9111a238b021453
Quelldatensatz
uspto-grants-2007_10
Patentnummer
US07279470B2

Verknüpfte Notizen

Wird geladen…