Potassium Hydroxide → 2-[(4-Bromophenyl)(pyridin-4-yl)methoxy]-4-methylpentanoic acid potassium salt

HRID 1180399Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1180399
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=2)[O:9][CH:10]([CH2:15][CH:16]([CH3:18])[CH3:17])[C:11]([O:13]C)=[O:12])=[CH:4][CH:3]=1.[OH-].[K+:26]>>[K+:26].[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[CH:20]=[CH:21][N:22]=[CH:23][CH:24]=2)[O:9][CH:10]([CH2:15][CH:16]([CH3:18])[CH3:17])[C:11]([O-:13])=[O:12])=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 14797Potassium HydroxideHCID 69473358Methyl 2-[(4-bromophenyl)(pyridin-4-yl)methoxy]-4-methylpentanoate

Produkt 1

HCID 694721682-[(4-Bromophenyl)(pyridin-4-yl)methoxy]-4-methylpentanoic acid potassium salt

Versuchsvorschrift

Using the same protocol as described in example 17, step 5, methyl 2-[(4-bromophenyl)(pyridin-4-yl)methoxy]-4-methylpentanoate from step 2 (293 mg, 0.75 mmol) was hydrolysed with potassium hydroxide. The solid residue obtained was used as such in the next step.

Aufarbeitung

  1. customThe solid residue obtained

Quellen und Nachweise

ORD-Eintrag
ord-b72668f28caa4aedb32fa74b63afb640
Quelldatensatz
uspto-grants-2007_10
Patentnummer
US07279478B2

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