Potassium Hydroxide → 2-[(4-Bromophenyl)(1,3-thiazol-2-yl)methoxy]-4-methylpentanoic acid potassium salt
Reaktionsgleichung
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[S:20][CH:21]=[CH:22][N:23]=2)[O:9][CH:10]([CH2:15][CH:16]([CH3:18])[CH3:17])[C:11]([O:13]C)=[O:12])=[CH:4][CH:3]=1.[OH-].[K+:25]>>[K+:25].[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[S:20][CH:21]=[CH:22][N:23]=2)[O:9][CH:10]([CH2:15][CH:16]([CH3:17])[CH3:18])[C:11]([O-:13])=[O:12])=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
Using the same protocol as described in example 17, step 5, methyl 2-[(4-bromophenyl)(1,3-thiazol-2-yl)methoxy]-4-methylpentanoate from step 2 (441 mg, 1.11 mmol) was hydrolysed with potassium hydroxide. The solid residue obtained was used as such in the next step.
Aufarbeitung
- customThe solid residue obtained
Quellen und Nachweise
- ORD-Eintrag
- ord-45dd58730ee647dc8c83dbe0ea6f7582