HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Bromine → 5-Bromo-2-methyl-4-(4-nitrophenyl)-1,3-thiazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Bromine | HCID 24408 | — |
| Edukt | 2-Methyl-4-(4-nitrophenyl)thiazole | HCID 193689 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | 5-Bromo-2-methyl-4-(4-nitrophenyl)-1,3-thiazole | HCID 68998100 | 60% |
Reaktionsschritte
Bromine (6 mmol) was added dropwise to a solution of 2-methyl-4-(4-nitrophenyl)-1,3-thiazole (5 mmol) in chloroform (20 mL) and the solution refluxed for 4 h. The solvent was evaporated and the product purified by crystallization from ether to afford the title compound (60%). ESMS [M+H]+: 300.2
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07282588B2 |
| Quelldatensatz | uspto-grants-2007_10 |
| ORD ID | ord-c828d164032c4ccc89f7f8adf90a7280 |
| Quellennotiz | uspto-grants-2007_10 |