HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3-Chlorophenyl)boronic acid → Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| Edukt | Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate | HCID 9914616 | — |
| Produkt | Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate | HCID 10231019 | 85,6% |
Reaktionsschritte
Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate (65 g) obtained in Example 1 and 3-chlorophenylboronic acid (23 g) were treated in the same manner as in Example 5 to give the title compound (59 g, yield 85%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07285551B2 |
| Quelldatensatz | uspto-grants-2007_10 |
| ORD ID | ord-24ca9bd67e234d8788ee1e4f91dc139b |
| Quellennotiz | uspto-grants-2007_10 |