Pentyltriphenylphosphonium bromide → (Butylmethylene)triphenylphosphorane

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a suspension of pentyltriphenylphosphonium bromide (5 equiv.) in dry THF (0.18M) at 0° C., under an argon atmosphere was added potassium bis(trimethylsilyl) amide (4.9 equiv.). The mixture was warmed to 10° C. and stirred for an additional 30 min to ensure complete formation of the orange ylide. The resulting slurry was used in the preparation of 1-(3,5-dimethoxyphenyl)-1-(hex-1-enyl)-cyclopentane.

Herkunft & Nachweise