Sodium Hydroxide → HCID 67362326, Verbindung
Reaktionsgleichung
C[O:2][C:3]([C:5]1[CH:9]=[C:8]([O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[N:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[F:21])[N:6]=1)=[O:4].[OH-].[Na+]>CO>[CH:12]1([CH2:11][O:10][C:8]2[N:7]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[F:21])[N:6]=[C:5]([C:3]([OH:4])=[O:2])[CH:9]=2)[CH2:13][CH2:14]1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The crude compound obtained in step 1 was dissolved in 10 ml of methanol. 1.4 ml of an aqueous 1 M solution of sodium hydroxide were added and the mixture was stirred overnight at room temperature. The solvent was removed in vacuo and the residue purified by preparative HPLC to give 102 mg (58%) of the title compound