Ethanol → Ethyl 1-(4-bromophenyl)cyclopropanecarboxylate
Reaktionsgleichung
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([C:11]([OH:13])=[O:12])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.S(=O)(=O)(O)O.[CH3:19][CH2:20]O>>[CH2:19]([O:12][C:11]([C:8]1([C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=2)[CH2:10][CH2:9]1)=[O:13])[CH3:20]Komponenten
4
Reaktionsbedingungen
- Temperatur
- 75 °C
Versuchsvorschrift
1-(4-Bromo-phenyl)-cyclopropanecarboxylic acid (5 g, 20.7 mmol) in EtOH (50 mL) was treated with sulfuric acid (2 mL), and the reaction was stirred at 75° C. for 1 hour. The mixture was worked up to give the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-3206036b48424a59b832e9da5398b8da
- Quelldatensatz
- uspto-grants-2014_03
- Patentnummer
- US08664220B2
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