Ammonium Acetate → CID 85348713

HRID 1187369Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1187369
O=[C:2]([CH2:9][CH2:10][CH2:11][CH3:12])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].C([O-])(=O)C.[NH4+:17]>C(O)C>[NH2:17][C:2]([CH2:9][CH2:10][CH2:11][CH3:12])=[CH:3][C:4]([O:6][CH2:7][CH3:8])=[O:5]

Komponenten

4

Edukt 2

HCID 517165Ammonium AcetateHCID 559036Ethyl 3-oxoheptanoate

Produkt 1

HCID 85348713CID 85348713Ausbeute 94,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Ethyl 3-oxoheptanoate (8.28 g, 48.13 mmol) and ammonium acetate (18.55 g, 240 mmol) were stirred in ethanol (80 ml) at room temperature for 96 hours. The solvent was evaporated and the residue stirred in dichloromethane (100 ml) for 30 minutes. The solid formed was filtered and the filtrate was washed with water (50 ml), saturated brine (50 ml) and dried over MgSO4 filtered and evaporated to give ethyl 3-aminohept-2-enoate (7.8 g, 94%) as a pale yellow oil.

Aufarbeitung

  1. customThe solvent was evaporated
  2. customThe solid formed
  3. filtrationwas filtered
  4. washthe filtrate was washed with water (50 ml), saturated brine (50 ml)
  5. dry with materialdried over MgSO4
  6. filtrationfiltered
  7. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-7bd8d1c5905c4082bc1b4fb5653e0cea
Quelldatensatz
uspto-grants-2014_03
Patentnummer
US08673938B2

Notizen zur Reaktion

Wird geladen…