4-(Trifluoromethyl)phenylboronic acid → 2-Methyl-4-(trifluoromethyl)-1-{[4'-(trifluoromethyl)-3-biphenylyl]methyl}-1H-indole-5-carbonitrile

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(Trifluoromethyl)phenylboronic acid	HCID 2734389	—
Edukt	1-[(3-Bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 67405035	—
Produkt	2-Methyl-4-(trifluoromethyl)-1-{[4'-(trifluoromethyl)-3-biphenylyl]methyl}-1H-indole-5-carbonitrile	HCID 86620703	—

Reaktionsschritte

Synthesized as described in Example 310D using 1-[(3-bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 318A) and [4-(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 459 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08673948B2
Quelldatensatz	uspto-grants-2014_03
ORD ID	ord-8a42d505da794663bf62dd9ba6488067
Quellennotiz	uspto-grants-2014_03