3-(Trifluoromethyl)phenylboronic acid → 2-Methyl-4-(trifluoromethyl)-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-3-yl}methyl)-1H-indole-5-carbonitrile

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3-(Trifluoromethyl)phenylboronic acid	HCID 2734388	—
Edukt	1-[(5-Chloro-1,2,4-thiadiazol-3-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 67405013	—
Produkt	2-Methyl-4-(trifluoromethyl)-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-3-yl}methyl)-1H-indole-5-carbonitrile	HCID 86620710	—

Reaktionsschritte

Synthesized as described in Example 327 using 1-[(5-chloro-1,2,4-thiadiazol-3-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 326) and [3-(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 467 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08673948B2
Quelldatensatz	uspto-grants-2014_03
ORD ID	ord-8d03d3be2ec84014818766c65b64ecee
Quellennotiz	uspto-grants-2014_03