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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1189777Erstellt: 27. Oktober 2026

2-Chloro-4-methoxybenzeneboronic acid → 8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)-phenyl]-amide

https://huagongshe.com/reaction/1189777

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-Chloro-4-methoxybenzeneboronic acidHCID 2773330—
Edukt3-(4-Ethylpiperazin-1-yl)anilineHCID 22330105—
Edukt8-(2-Chloro-5-methoxy-phenyl)quinoxaline-5-carboxylic acidHCID 66914608—
Produkt8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)-phenyl]-amideHCID 44515980—

Reaktionsschritte

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 3-(4-ethylpiperazin-1-yl)-aniline (Step 2.1) and 8-(2-chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid. The latter compound was synthesized as described in Steps 1.2-1.7 but using 2-chloro-4-methoxyphenylboronic acid in Step 1.4. Title compound: ESI-MS: 502.1 [M]+; tR=3.57 min (System 3).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08674099B2
Quelldatensatzuspto-grants-2014_03
ORD IDord-f7c4f7266cab4b28a0104360d0ab2d1b
Quellennotizuspto-grants-2014_03