Ammonia → 4-Ethyl-7-(4-nitro-phenylazo)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

HRID 1190779Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1190779
F[B-](F)(F)F.[N+:6]([C:9]1[CH:14]=[CH:13][C:12]([N+:15]#[N:16])=[CH:11][CH:10]=1)([O-:8])=[O:7].[CH2:17]([N:19]1[C:24]2[CH:25]=[C:26]([OH:29])[CH:27]=[CH:28][C:23]=2[O:22][CH2:21][CH2:20]1)[CH3:18].N>S(=O)(=O)(O)O>[CH2:17]([N:19]1[C:24]2[CH:25]=[C:26]([OH:29])[C:27]([N:16]=[N:15][C:12]3[CH:11]=[CH:10][C:9]([N+:6]([O-:8])=[O:7])=[CH:14][CH:13]=3)=[CH:28][C:23]=2[O:22][CH2:21][CH2:20]1)[CH3:18]

Komponenten

5

Edukt 3

HCID 222AmmoniaHCID 680064-Nitrobenzenediazonium tetrafluoroborateHCID 687776134-Ethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

Produkt 1

HCID 1363315334-Ethyl-7-(4-nitro-phenylazo)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

p-Nitrobenzenediazonium tetrafluoroborate (0.251 g, 1.06 mmol) was dissolved in 10% sulfuric acid (10 ml) and added to a methanolic solution (10 ml) of 50a (0.19 g, 1.06 mmol). The solution turned red immediately. The reaction mixture was neutralized with ammonia. The red precipitate was filtered to give quantitative yield of the product. ES-HRMS [M−H]− 327.1428. Calcd for (C16H15N4O4): 327.1094.

Aufarbeitung

  1. filtrationThe red precipitate was filtered

Quellen und Nachweise

ORD-Eintrag
ord-3f8f00a583894ec9a8897db4f9fb689d
Quelldatensatz
uspto-grants-2014_03
Patentnummer
US08679776B2

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