2,4-Dichlorobenzenethiol → 2-(2,4-Dichlorophenyl)sulfanyl-5-methylsulfonyl-3-nitro-thiophene
Reaktionsgleichung
Br[C:2]1[S:3][C:4]([S:10]([CH3:13])(=[O:12])=[O:11])=[CH:5][C:6]=1[N+:7]([O-:9])=[O:8].[Cl:14][C:15]1[CH:20]=[C:19]([Cl:21])[CH:18]=[CH:17][C:16]=1[SH:22]>>[Cl:14][C:15]1[CH:20]=[C:19]([Cl:21])[CH:18]=[CH:17][C:16]=1[S:22][C:2]1[S:3][C:4]([S:10]([CH3:13])(=[O:12])=[O:11])=[CH:5][C:6]=1[N+:7]([O-:9])=[O:8]Komponenten
3
Versuchsvorschrift
Prepared by a similar procedure to that described as in Step D for example 22 from the 2-bromo-5-methylsulfonyl-3-nitro-thiophene (148 mg, 0.52 mmol) and 2,4-dichlorobenzenethiol (100 mg, 0.56 mmol) to afford the title product as a solid (50 mg, 25% yield). 1H NMR (400 MHz, d6-DMSO) δ: 8.35 (1H, s), 8.10 (1H, m), 8.20 (1H, m), 7.74 (1H, m), 3.42 (3H, s). MS m/z: 381.81 [M+H]+.
Aufarbeitung
- customPrepared by a similar procedure to that