2,3-Dimethoxybenzylamine → HCID 60207335, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][O:22][C:23]1[C:30]([O:31][CH3:32])=[CH:29][CH:28]=[CH:27][C:24]=1[CH2:25][NH2:26]>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:26][CH2:25][C:24]2[CH:27]=[CH:28][CH:29]=[C:30]([O:31][CH3:32])[C:23]=2[O:22][CH3:21])=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]Komponenten
3
Versuchsvorschrift
Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (160 mg, 0.43 mmol) and 2,3-dimethoxy benzylamine (87 mg, 0.52 mmol). The title compound was obtained as a solid (80 mg, 37% yield). 1H NMR (400 MHz, d6-DMSO) δ: 9.25 (1H, m), 8.98 (2H, m), 8.51 (1H, s), 6.99 (2H, m), 6.82 (1H, m), 4.38 (2H, m), 3.78 (3H, s), 3.71 (3H, s). MS m/z: 498.29, 500.27 [M+H]+.
Aufarbeitung
- customPrepared