3-[3-(Aminomethyl)phenoxy]-N,N-dimethylpropan-1-amine → HCID 60207362, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[NH2:21][CH2:22][C:23]1[CH:24]=[C:25]([CH:33]=[CH:34][CH:35]=1)[O:26][CH2:27][CH2:28][CH2:29][N:30]([CH3:32])[CH3:31]>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:21][CH2:22][C:23]2[CH:35]=[CH:34][CH:33]=[C:25]([O:26][CH2:27][CH2:28][CH2:29][N:30]([CH3:31])[CH3:32])[CH:24]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]Komponenten
3
Versuchsvorschrift
Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and 3-[3-(aminomethyl)phenoxy]-N,N-dimethyl-propan-1-amine (25.0 mg, 0.12 mmol). The title compound was obtained as a solid (35.4 mg, 65% yield). MS m/z: 541.06, 543.05 [M+H]+.
Aufarbeitung
- customPrepared