m-Chloroperbenzoic acid → [{1-(6-Methyl-1,3-benzodioxol-5-yl)ethyl}sulfinyl]acetic acid

HRID 1195264Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1195264
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH3:12][C:13]1[C:14]([CH:22]([S:24][CH2:25][C:26]([OH:28])=[O:27])[CH3:23])=[CH:15][C:16]2[O:20][CH2:19][O:18][C:17]=2[CH:21]=1>C(Cl)(Cl)Cl>[CH3:12][C:13]1[C:14]([CH:22]([S:24]([CH2:25][C:26]([OH:28])=[O:27])=[O:9])[CH3:23])=[CH:15][C:16]2[O:20][CH2:19][O:18][C:17]=2[CH:21]=1

Komponenten

4

Edukt 2

HCID 70297m-Chloroperbenzoic acidHCID 14514909[{1-(6-Methyl-1,3-benzodioxol-5-yl)ethyl}thio]acetic acid

Produkt 1

HCID 14514921[{1-(6-Methyl-1,3-benzodioxol-5-yl)ethyl}sulfinyl]acetic acidAusbeute 11,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

1.7 g of 80% m-chloroperbenzoic acid was added to a solution of 2.0 g of [{1-(6-methyl-1,3-benzodioxol-5-yl)ethyl}thio]acetic acid in 40 ml of chloroform under cooling with ice. The mixture was stirred at room temperature overnight and a crystalline insoluble matter was recovered by filtration and washed with ether to obtain 0.24 g of the intended compound (as a single diastereomer) in the form of white crystals.

Aufarbeitung

  1. temperatureunder cooling with ice
  2. filtrationa crystalline insoluble matter was recovered by filtration
  3. washwashed with ether

Quellen und Nachweise

ORD-Eintrag
ord-802ebf6a2fa24f07a538f59e2a09b94a
Quelldatensatz
uspto-grants-1992_05
Patentnummer
US05110956

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