[C:1](=O)([O-])[O-].[K+].[K+].[CH2:7]([NH2:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH2:15](Cl)[CH:16]=[CH:17][CH2:18][CH2:19][CH3:20].[Cl-].[Na+]>CN(C)C=O>[CH2:7]([NH:14][CH2:15][CH:16]=[CH:17][CH2:18][CH2:19][CH2:20][CH3:1])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=113 g of potassium carbonate and 20 g of benzylamine were added to 25 ml of N,N-dimethylformamide and, further, 20 g of 2-hexenyl chloride was added and stirred at 100°-120° C. for one hour. After the reaction, 100 ml of an aqueous solution of sodium chloride was added, extracted with ethyl acetate and dried with anhydrous sodium sulfate. After concentration in an evaporator, it was subjected to silica gel column chromatography (hexane/ethyl acetate=1/1, v/v) to obtain 18 g of the aimed compound.
Wird geladen…
