Triethyl 4-phosphonocrotonate, mixture of isomers → (2E,4E) N-Isobutyl 12-(6-bromo-2-quinolinyloxy)-dodeca-2,4-dienamide
Reaktionsgleichung
BrC1C=C2C(=CC=1)N=C(O)C=C2.[CH2:13]([NH:17][C:18](=[O:43])[CH:19]=[C:20](C)[CH:21]=[CH:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][O:30][C:31]1[CH:40]=[CH:39][C:38]2[C:33](=[CH:34][CH:35]=[C:36]([Br:41])[CH:37]=2)[N:32]=1)[CH:14]([CH3:16])[CH3:15].CCOC(/C=C/CP(OCC)(OCC)=O)=O>>[CH2:13]([NH:17][C:18](=[O:43])/[CH:19]=[CH:20]/[CH:21]=[CH:22]/[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][O:30][C:31]1[CH:40]=[CH:39][C:38]2[C:33](=[CH:34][CH:35]=[C:36]([Br:41])[CH:37]=2)[N:32]=1)[CH:14]([CH3:16])[CH3:15]Komponenten
4
Versuchsvorschrift
Starting from 6-bromo-2-hydroxyquinoline (prepared as for Compound 17) and triethyl 4-phosphonocrotonate.