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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1196829Erstellt: 26. Oktober 2026

N-acetyl-L-methionine → 21-[2-(Acetylamino)-4-methylthio-1-oxobutylthio]-9-fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione

https://huagongshe.com/reaction/1196829

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktN-acetyl-L-methionineHCID 448580—
EduktHCID 131717396HCID 131717396—
Produkt21-[2-(Acetylamino)-4-methylthio-1-oxobutylthio]-9-fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dioneHCID 8849435853,4%

Reaktionsschritte

The title compound (0.38 gm) was prepared from 9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione-21-thiol (0.50 gm) and N-acetyl-L-methionine (0.70 gm) in the same manner as in Synthetic Example 1.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05116829
Quelldatensatzuspto-grants-1992_05
ORD IDord-2f89926fca1d4e44a5c3e2e4e431581b
Quellennotizuspto-grants-1992_05