N'-t-butyl-N'-(3-methylbenzoyl)hydrazine → N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

HRID 1197298

Reaktionsgleichung

Reaktionsgleichung von HRID 1197298
[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH2:6])([CH3:4])([CH3:3])[CH3:2].[C:16]1([CH:22]([CH:26]([CH3:29])[CH2:27][CH3:28])[C:23](Cl)=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C1(C)C=CC=CC=1.[OH-].[Na+]>[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH:6][C:23](=[O:24])[CH:22]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH:26]([CH3:29])[CH2:27][CH3:28])([CH3:4])([CH3:3])[CH3:2]

Komponenten

5

Edukt 2

HCID 15452040N'-t-butyl-N'-(3-methylbenzoyl)hydrazineHCID 218860263-Methyl-2-phenylvaleryl chloride

Produkt 1

HCID 15452019N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 14798Sodium HydroxideKatalysatorHCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a stirred suspension of N'-t-butyl-N'-(3toluoyl)hydrazine (0.7 g) in toluene (10 ml) and aqueous sodium hydroxide (12 drops of 50% aqueous sodium hydroxide) was added dropwise 2-phenyl-3-methyl-pentanoyl chloride (1.0 g). The reaction mixture was stirred overnight, diluted with hexanes and the solids filtered. The solids were washed with hexane and air dried.

Aufarbeitung

  1. filtrationthe solids filtered
  2. washThe solids were washed with hexane and air
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-42a113d0cf8b4d84ba61a9873e270a79
Quelldatensatz
uspto-grants-1992_05
Patentnummer
US05117057

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