HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine → Gla-aht
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine | HCID 1049 | — |
| Edukt | 2,5-Methano-5H,9H-pyrimido(2,1-b)(1,5,3)dioxazepin-9-one, 2,3-dihydro-3-(hydroxymethyl)-8-methyl-, (2R,3R,5R)- | HCID 457982 | — |
| Produkt | Gla-aht | HCID 6475485 | — |
Reaktionsschritte
Anhydrothymidine (0.520 g, 2.319 mmol, as a dry white powder) was dissolved in anhydrous pyridine (10 ml) under an atmosphere of dry nitrogen, and to this stirred solution at room temperature was added GLA acid chloride (0.900 g, 3.02 mmol). Stirring was continued overnight after which period, TLC indicated complete loss of the starting material. The pyridine was
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05276020 |
| Quelldatensatz | uspto-grants-1994_01 |
| ORD ID | ord-f4b0413425a043e68a1a6429d3d68dea |
| Quellennotiz | uspto-grants-1994_01 |