Methylamine → HCID 19104677, Verbindung
Reaktionsgleichung
[C:1]1([S:7]([CH2:10][CH2:11][CH2:12]O)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC1C=CC(S([O-])(=O)=O)=CC=1.[CH3:25][NH2:26]>>[CH3:25][NH:26][CH2:12][CH2:11][CH2:10][S:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:9])=[O:8]Komponenten
3
Versuchsvorschrift
25.5 g (71.9 mmol) of 3-(phenylsulfonyl)-1-propanol-4-methylbenzenesulfonate [see H. O. Fong et al., Can. J. Chem., 57, 1206 (1979)]were dissolved in 45 ml of methylamine and stirred for 24 hours at 80° and 1000 kpa. Thereafter, the methylamine was evaporated under reduced pressure, the residue was poured into ice-water and extracted with methylene chloride. The methylene chloride extracts were dried over potassium carbonate and evaporated under reduced pressure, whereby there were obtained 14.1 g of N-methyl-3-(phenylsulfonyl)propylamine as an oil, MS: 214 (M+H)+.
Aufarbeitung
- customThereafter, the methylamine was evaporated under reduced pressure
- additionthe residue was poured into ice-water
- extractionextracted with methylene chloride