Trifluoroacetic acid → 2-[1-(2-Hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-N-{1-[4-hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-acetamide

Reaktionsgleichung

[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32].[NH:1]1[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH2:22][CH2:23][OH:24])[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]23)=[O:25])[CH2:4]1.[OH:33][C:34]1([c:41]2[cH:42][n:43][c:44]([O:47][CH3:48])[cH:45][cH:46]2)[CH2:35][CH2:36][C:37](=[O:40])[CH2:38][CH2:39]1>>[N:1]1([CH:37]2[CH2:36][CH2:35][C:34]([OH:33])([c:41]3[cH:42][n:43][c:44]([O:47][CH3:48])[cH:45][cH:46]3)[CH2:39][CH2:38]2)[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH2:22][CH2:23][OH:24])[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]23)=[O:25])[CH2:4]1