2-Oxocyclohexanepropiononitrile → 3-(3-Chloro-2-oxo-cyclohexyl)-propionitrile

HRID 12030

Reaktionsgleichung

[O:1]=[C:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[CH2:8][CH2:9][C:10]#[N:11].C(C1CCCC([Cl:22])C1=O)(C)(C)C>>[Cl:22][CH:7]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:8][CH2:9][C:10]#[N:11])[C:2]1=[O:1]

Komponenten

Edukt 2

HCID 962232-Oxocyclohexanepropiononitrile

HCID 686809722-Tert-butyl-6-chlorocyclohexanone

Produkt 1

HCID 686835783-(3-Chloro-2-oxo-cyclohexyl)-propionitrile

Versuchsvorschrift

The chlorination of 2-oxo-1-cyclohexanepropionitrile takes place in a manner similar to that described above for the preparation of 2-tert-butyl-6-chloro-cyclohexanone. The title compound is reacted as a crude product without further characterization.

Quellen und Nachweise

ORD-Eintrag: ord-7fd1a39939ab4c2897ab649df14746c2
Quelldatensatz: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07727979B2

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