Tetrahydrofuran → 2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-5-(hydroxy-phenyl-methyl)-indole-1-carboxylic acid tert-butyl ester

Reaktionsgleichung

[Br:34][Mg:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](-[c:19]2[c:20]3[c:21]([n:22]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[n:23]2)[cH:31][cH:32][s:33]3)[cH:10][c:11]2[cH:12][c:13]([CH:17]=[O:18])[cH:14][cH:15][c:16]12.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](-[c:19]2[c:20]3[c:21]([n:22]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[n:23]2)[cH:31][cH:32][s:33]3)[cH:10][c:11]2[cH:12][c:13]([CH:17]([OH:18])[c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[cH:14][cH:15][c:16]12